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In this foreboding letter, former president Thomas Jefferson warned Representative John Holmes that the alarming issue of slavery could not be staved off forever. In words foreshadowing the Civil War, Jefferson predicted the issue once loosed would ignite the nation in violence and destruction.
…this momentous question, like a fire bell in the night, awakened and filled me with terror. I considered it at once as the knell of the Union.
Manuscript Division, Library of Congress